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Are Front-Loading Washing Machines Death Traps for Kids?

Ebola death toll in DR Congo rises to 180

A Congolese health worker administers the Ebola vaccine to a boy who had contact with an Ebola sufferer in the village of Mangina in North Kivu province of the Democratic Republic of Congo, August 18, 2018. © foto: REUTERS/Olivia Acland

Noel Gallagher: il video di “The Death of you and me“. il suo primo singola da solista

da oggi in anteprima sul web il video di "THE DEATH OF YOU AND ME” IL PRIMO SINGOLO CHE ANTICIPA LA PUBBLICAZIONE DEL SUO PRIMO ALBUM DA SOLISTA “NOEL GALLAGHER’S HIGH FLYING BIRDS“

Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Resp

Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells.Sabrina Rotolo 1, Simona Ceccarelli 1, Ferdinando Romano 1, Luigi Frati 1,2, Cinzia Marchese 1, Antonio Angeloni 1* 1 Dipartimento di Medicina Sperimentale, Universita` Sapienza di Roma, Roma, Italy, 2 Istituto Neurologico Mediterraneo ‘‘Neuromed, Pozzilli, ItalyAbstract : BackgroundKeratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGFR signaling have been linked to the pathogenesis of different epithelial tumors. It has been also hypothesized that its specific ligand, KGF, might contribute to the development of resistance to 5-fluorouracil (5-FU) in epithelial cancers and tamoxifen in estrogen-positive breast cancers.Abstract : Methodology/Principal FindingsSmall interfering RNA was transfected into a human keratinocyte cell line (HaCaT), a breast cancer derived cell line (MCF-7) and a keratinocyte primary culture (KCs) to induce selective downregulation of KGFR expression. A strong and highly specific reduction of KGFR expression was observed at both RNA (reduction = 75.7%, P = 0.009) and protein level. KGFR silenced cells showed a reduced responsiveness to KGF treatment as assessed by measuring proliferation rate (14.2% versus 39.0% of the control cells, P

Neuron-specific knock-down of SMN1 causes neuron degeneration and death through an apoptotic mechanism

Death Made In America

Wondering if your conscience is still anesthetized Mohammed Daud Miraki, MA, MA, PhD Exclusive To Rense.com Mdmiraki@ameritech.net

Federal High Court Sentences Genocide Convict to Death

Mother jailed for killing son, 3

A 33-year-old Italian mother has been sentenced to 30 years in jail for bludgeoning to death her three-year-old son, a crime she has always denied.

DARK TRANQUILLITY in concerto

Sono considerati i capostipiti del rinnovato movimento death metal scandinavo Da Goteborg portano in Italia il loro sound fatto di melodia, passione e impatto

Il death metal personale del gruppo dal sound roccioso ed emozionante [ NOVEMBRE ]

Black Hawks crash death toll rises to 17